Downloads

  • Mutagenesis Data

    All data from the Mutagenesis tab including EC50s, effect on channel function, and mutant vs variant distinction.

    Download

  • Natural Variant Data

    All data from Natural Variant tab, including field sites, NCBI accessions, and schistosome life stage.

    Download

  • All Data

    Spreadsheet with combined mutagenesis and natural variant data.

    Download

Published Data Sources

Extensive transmission and variation in a functional receptor for praziquantel resistance in endemic Schistosoma mansoni

Berger, D. J., Park, S. K., Crellen, T., Vianney, T. J., Kabatereine, N. B., Cotton, J. A., Sanya, R., Elliot, A., Tukahebwa, E. M., Adriko, M., Standley, C. J., Gouvras, A., Kinung'hi, S., Haas, H., Rabone, M., Emery, A., Lamberton, P. H. L., Webster, B. L., Allan, F., Buddenborg, S., … Webster, J. P. (2024). bioRxiv : the preprint server for biology, 2024.08.29.610291. https://doi.org/10.1101/2024.08.29.610291

Mechanism of praziquantel action at a parasitic flatworm ion channel

Park, S. K., Friedrich, L., Yahya, N. A., Rohr, C. M., Chulkov, E. G., Maillard, D., Rippmann, F., Spangenberg, T., & Marchant, J. S. (2021). Science translational medicine, 13(625), eabj5832. https://doi.org/10.1126/scitranslmed.abj5832

Updated 12/11/24